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Paper · 2306.06138 · 2023

Extraction and Recovery of Spatio-Temporal Structure in Latent Dynamics Alignment with Diffusion Models

arXiv · PDF · Open in the Atlas

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alexwangntl/erdiff canonical 0 of 6
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Conv1d_with_init Not yet run alexwangntl/erdiff/models/diffusion.py
code served (permissive licence) · get_code("6bd07470db31cdd1")
create_dir_dict Not yet run alexwangntl/erdiff/utils/utils_torch.py
code served (permissive licence) · get_code("6f24cbc25ba26487")
get_logger Not yet run alexwangntl/erdiff/utils/utils_torch.py
code served (permissive licence) · get_code("c969dec60bfb5ba4")
get_torch_trans Not yet run alexwangntl/erdiff/models/diffusion.py
code served (permissive licence) · get_code("fdfe977803809a23")
logger_performance Not yet run alexwangntl/erdiff/utils/utils_torch.py
code served (permissive licence) · get_code("68ce79c3f51af94d")
sinusoidal_positional_encoding Not yet run alexwangntl/erdiff/models/diffusion.py
code served (permissive licence) · get_code("d90fbbcbbbbc2f89")

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Abstract

In the field of behavior-related brain computation, it is necessary to align raw neural signals against the drastic domain shift among them. A foundational framework within neuroscience research posits that trial-based neural population activities rely on low-dimensional latent dynamics, thus focusing on the latter greatly facilitates the alignment procedure. Despite this field's progress, existing methods ignore the intrinsic spatio-temporal structure during the alignment phase. Hence, their solutions usually lead to poor quality in latent dynamics structures and overall performance. To tackle this problem, we propose an alignment method ERDiff, which leverages the expressivity of the diffusion model to preserve the spatio-temporal structure of latent dynamics. Specifically, the latent dynamics structures of the source domain are first extracted by a diffusion model. Then, under the guidance of this diffusion model, such structures are well-recovered through a maximum likelihood alignment procedure in the target domain. We first demonstrate the effectiveness of our proposed method on a synthetic dataset. Then, when applied to neural recordings from the non-human primate motor cortex, under both cross-day and inter-subject settings, our method consistently manifests its capability of preserving the spatiotemporal structure of latent dynamics and outperforms existing approaches in alignment goodness-of-fit and neural decoding performance.

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