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Paper · 2310.19224 · NeurIPS · 2023

CHAMMI: A benchmark for channel-adaptive models in microscopy imaging

Bryan Plummer, Siqi Wang, Chau Pham, Zitong Chen, Michael Doron, Nikita Moshkov, Juan Caicedo

arXiv · PDF · Open in the Atlas

Code that ran

We lifted 6 functions out of this paper's own repositories and ran 5 of them in a sandbox. "Ran" means the function executed on a synthesized input and returned a value. It is not a reproduction of the paper's results.

RepositoryRoleRan
chaudatascience/channel_adaptive_models canonical 3 of 4
broadinstitute/MorphEm canonical 2 of 2
FunctionStatusWhere it lives
conv1x1 Ran chaudatascience/channel_adaptive_models/models/model_utils.py
code served (permissive licence) · get_code("d37367093dc7b4b1")
conv3x3 Ran chaudatascience/channel_adaptive_models/models/model_utils.py
code served (permissive licence) · get_code("75d042751b02d666")
create_pad Ran broadinstitute/MorphEm/morphem/feature_extraction.py
code served (permissive licence) · get_code("fb4a634bb601c6bb")
fold_channels Ran broadinstitute/MorphEm/morphem/folded_dataset.py
code served (permissive licence) · get_code("f5ddcacca60f8646")
get_module Ran chaudatascience/channel_adaptive_models/models/convnext_base_miro.py
code served (permissive licence) · get_code("c8980fa1301b0ca7")
toggle_grad Not yet run chaudatascience/channel_adaptive_models/models/model_utils.py
code served (permissive licence) · get_code("01e6af61e53c2cf9")

Repositories linked to this paper

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Abstract

Most neural networks assume that input images have a fixed number of channels (three for RGB images). However, there are many settings where the number of channels may vary, such as microscopy images where the number of channels changes depending on instruments and experimental goals. Yet, there has not been a systemic attempt to create and evaluate neural networks that are invariant to the number and type of channels. As a result, trained models remain specific to individual studies and are hardly reusable for other microscopy settings. In this paper, we present a benchmark for investigating channel-adaptive models in microscopy imaging, which consists of 1) a dataset of varied-channel single-cell images, and 2) a biologically relevant evaluation framework. In addition, we adapted several existing techniques to create channel-adaptive models and compared their performance on this benchmark to fixed-channel, baseline models. We find that channel-adaptive models can generalize better to out-of-domain tasks and can be computationally efficient. We contribute a curated dataset 1 and an evaluation API 2 to facilitate objective comparisons in future research and applications.

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